DKKL1 Antibody (PACO42550)
- SKU:
- PACO42550
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
DKKL1 Antibody (PACO42550)
The DKKL1 Polyclonal Antibody (PAC042550) is a valuable tool for researchers studying DKKL1, a protein involved in Wnt signaling pathways and development. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot and immunohistochemistry applications. It binds specifically to the DKKL1 protein, allowing for accurate detection and analysis in a variety of cell types.DKKL1, also known as Dickkopf-like protein 1, plays a crucial role in regulating Wnt signaling, which is essential for embryonic development and tissue homeostasis. Dysregulation of Wnt signaling has been implicated in various diseases, including cancer and developmental disorders, making DKKL1 a promising target for research.
By studying the function and expression of DKKL1, researchers can gain insight into its role in disease progression and potentially identify new therapeutic strategies.Overall, the DKKL1 Polyclonal Antibody is a valuable tool for researchers investigating the function of DKKL1 in Wnt signaling pathways and its implications in disease. Its high specificity and reliability make it ideal for immunological and cancer research studies, providing important insights into the mechanisms underlying these conditions.
| Antibody Name: | DKKL1 Antibody (PACO42550) |
| Antibody SKU: | PACO42550 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Dickkopf-like protein 1 protein (31-242AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO42550 at dilution of 1:100. |
| Background: | extracellular space, signal transducer activity, anatomical structure morphogenesis, mitophagy in response to mitochondrial depolarization, positive regulation of defense response to virus by host, signal transduction, xenophagy |
| Synonyms: | Dickkopf-like protein 1 (Cancer/testis antigen 34) (CT34) (Protein soggy-1) (SGY-1), DKKL1, SGY1 |
| UniProt Protein Function: | DKKL1: |
| UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA); Secreted, signal peptide; Cell development/differentiation; Secreted Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: extracellular space Molecular Function:signal transducer activity Biological Process: anatomical structure morphogenesis; positive regulation of defense response to virus by host; positive regulation of fat cell differentiation; signal transduction |
| NCBI Summary: | The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2010] |
| UniProt Code: | Q9UK85 |
| NCBI GenInfo Identifier: | 308818218 |
| NCBI Gene ID: | 27120 |
| NCBI Accession: | NP_001184230.1 |
| UniProt Related Accession: | Q9UK85 |
| Molecular Weight: | 27,007 Da |
| NCBI Full Name: | dickkopf-like protein 1 isoform 2 |
| NCBI Synonym Full Names: | dickkopf like acrosomal protein 1 |
| NCBI Official Symbol: | DKKL1Â Â |
| NCBI Official Synonym Symbols: | SGY; CT34; SGY1; SGY-1Â Â |
| NCBI Protein Information: | dickkopf-like protein 1 |
| UniProt Protein Name: | Dickkopf-like protein 1 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 34; CT34; Protein soggy-1; SGY-1 |
| Protein Family: | Dickkopf-like protein |
| UniProt Gene Name: | DKKL1Â Â |
| UniProt Entry Name: | DKKL1_HUMAN |
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