The DKK3 Rabbit Monoclonal Antibody (CAB3892) is a cutting-edge tool for researchers studying the function of DKK3, a key player in the Wnt signaling pathway involved in cell proliferation and differentiation. This antibody, developed from rabbit monoclonal sources, exhibits high specificity and sensitivity for detecting DKK3 protein in human samples, making it ideal for a variety of research applications including Western blotting.DKK3, also known as Dickkopf-3, is a secreted protein that acts as a tumor suppressor by inhibiting tumor cell growth and metastasis. Its dysregulation has been implicated in various cancers, making it a promising target for therapeutic interventions.
The ability of the DKK3 Rabbit Monoclonal Antibody to specifically bind and detect DKK3 protein enables researchers to explore its role in cancer development and progression, paving the way for potential treatment strategies targeting this pathway. With its superb performance and reliability in detecting DKK3, the DKK3 Rabbit Monoclonal Antibody (CAB3892) is an invaluable tool for advancing research in oncology and molecular biology. Explore the intricate roles of DKK3 in cancer biology and uncover new avenues for therapeutic interventions with this high-quality antibody.
Product Name:
DKK3 Rabbit Monoclonal Antibody
SKU:
CAB3892
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-350 of human DKK3 (Q9UBP4) (NP_056965.3)
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
Purification Method:
Affinity purification
Gene ID:
27122
Clone Number:
ARC0861
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DKK3 Rabbit mAb (CAB3892) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
