The DKK3 Polyclonal Antibody (CAB2527), it is a valuable tool for researchers studying the DKK3 protein, which is involved in various cellular processes, including cell proliferation and differentiation. This antibody was generated in rabbits and is specifically designed to react with human samples, making it ideal for use in Western blot applications.The DKK3 protein is a member of the Dickkopf family, known for its role in the Wnt signaling pathway, which is crucial for cell development and tissue homeostasis. Dysregulation of DKK3 has been implicated in diseases such as cancer, cardiovascular disorders, and neurological conditions.
By using this antibody, researchers can accurately detect and analyze the expression of DKK3 in different cell types, providing valuable insights into its function and potential therapeutic applications.With its high specificity and sensitivity, the DKK3 Polyclonal Antibody (CAB2527) is a reliable tool for investigating the role of DKK3 in various physiological and pathological processes, making it a valuable asset for studies in cancer biology, developmental biology, and regenerative medicine.
Product Name:
DKK3 Rabbit Polyclonal Antibody
SKU:
CAB2527
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-200 of human DKK3 (NP_056965.3).
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
Purification Method:
Affinity purification
Gene ID:
27122
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using DKK3 Rabbit pAb (CAB2527) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
