DKK2 Rabbit Polyclonal Antibody (CAB14874)
- SKU:
- CAB14874
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | DKK2 Rabbit Polyclonal Antibody |
SKU: | CAB14874 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human DKK2 (NP_055236.1). |
Sequence: | CMVC RRKK KRCH RDGM CCPS TRCN NGIC IPVT ESIL TPHI PALD GTRH RDRN HGHY SNHD LGWQ NLGR PHTK MSHI KGHE GDPC LRSS DCIE GFCC ARHF WTKI CKPV LHQG EVCT KQRK KGSH GLEI FQRC DCAK GLSC KVWK DATY SSKA RLHV CQKI |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:100 - 1:500 |
Synonyms: | DKK-2; DKK2 |
Positive Sample: | A-549,NCI-H460 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 28kDa |
Observed MW: | 30kDa |
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).
Purification Method: | Affinity purification |
Gene ID: | 27123 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |