DKC1 Rabbit Monoclonal Antibody (CAB4407)
- SKU:
- CAB4407
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CBF5
- DKC
- DKCX
- NAP57
- NOLA4
- XAP101
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DKC1 Rabbit Monoclonal Antibody |
SKU: | CAB4407 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human DKC1 (O60832). |
Sequence: | VMKD SAVN AICY GAKI MLPG VLRY EDGI EVNQ EIVV ITTK GEAI CMAI ALMT TAVI STCD HGIV AKIK RVIM ERDT YPRK WGLG PKAS QKKL MIKQ GLLD K |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | DKC; CBF5; DKCX; NAP57; NOLA4; XAP101; DKC1 |
Positive Sample: | PC-3,Mouse brain,Mouse heart,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cajal body, Cytoplasm, Nucleus, nucleolus. |
Calculated MW: | 58kDa |
Observed MW: | 60kDa |
This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1736 |
Clone Number: | ARC1063 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |