The DIXDC1 Polyclonal Antibody (CAB15542) is a valuable tool for researchers studying DIXDC1, a key regulator of dendritic spine development and synaptic plasticity in the brain. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By targeting the DIXDC1 protein, this antibody allows for precise detection and analysis in various cell types, making it an ideal choice for studies in neuroscience and neurodevelopmental disorders.DIXDC1, also known as Disheveled-Axin Domain Containing 1, plays a crucial role in neuronal development and function by modulating Wnt signaling pathways.
Dysregulation of DIXDC1 has been linked to a range of neurological disorders, including autism spectrum disorders and schizophrenia. By investigating the function of DIXDC1, researchers can gain insights into the underlying mechanisms of these conditions and potentially identify new therapeutic targets for treatment.Overall, the DIXDC1 Polyclonal Antibody (CAB15542) offers researchers a reliable tool for studying DIXDC1 and its role in brain development and neurological disorders. Its specificity and sensitivity make it a valuable asset for furthering our understanding of neurobiology and potential therapeutic interventions.
Product Name:
DIXDC1 Rabbit Polyclonal Antibody
SKU:
CAB15542
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 173-472 of human DIXDC1 (NP_219493.1).
The protein encoded by this gene is a positive regulator of the Wnt signaling pathway. The encoded protein is found associated with gamma tubulin at the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
85458
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DIXDC1 Rabbit pAb (CAB15542) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60S.
