DISP1 Rabbit Polyclonal Antibody (CAB14946)
- SKU:
- CAB14946
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | DISP1 Rabbit Polyclonal Antibody |
SKU: | CAB14946 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1325-1524 of human DISP1 (NP_116279.2). |
Sequence: | FVHP ITHI HHCP CLQG RVKP AGMQ NSLP RNFF LHPV QHIQ AQEK IGKT NVHS LQRS IEEH LPKM AEPS SFVC RSTG SLLK TCCD PENK QREL CKNR DVSN LESS GGTE NKAG GKVE LSLS QTDA SVNS EHFN QNEP KVLF NHLM GEAG CRSC PNNS QSCG RIVR VKCN SVDC QMPN MEAN VPAV LTHS ELSG ESLL IKTL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DISPA; DISP1 |
Positive Sample: | HT-29,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 171kDa |
Observed MW: | 180kDa |
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo.
Purification Method: | Affinity purification |
Gene ID: | 84976 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |