The DISC1 Rabbit Monoclonal Antibody (CAB4678) is a cutting-edge tool for researchers studying DISC1, a key protein involved in neuronal development and psychiatric disorders. This antibody, developed using rabbit monoclonal technology, offers high specificity and affinity for human samples, making it an ideal choice for research in neuroscience and mental health.DISC1, also known as disrupted in schizophrenia 1, is a crucial player in various cellular processes, including neuronal migration, neurite outgrowth, and synaptic transmission. Dysregulation of DISC1 has been linked to a range of psychiatric conditions, including schizophrenia, bipolar disorder, and major depressive disorder.
By targeting DISC1 with this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these complex disorders.This antibody is validated for use in Western blot applications, allowing for precise detection and analysis of DISC1 expression in various cell types and experimental conditions. Its versatility and sensitivity make it a valuable tool for both basic research and drug discovery efforts aimed at developing novel treatments for psychiatric illnesses. Unlock the mysteries of DISC1 and advance our understanding of psychiatric disorders with the DISC1 Rabbit Monoclonal Antibody (CAB4678).
Product Name:
DISC1 Rabbit Monoclonal Antibody
SKU:
CAB4678
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DISC1 (Q9NRI5).
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
27185
Clone Number:
ARC1089
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DISC1 Rabbit mAb (CAB4678) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
