DISC1 Rabbit Polyclonal Antibody (CAB2898)
- SKU:
- CAB2898
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Neuroscience
Frequently bought together:
Description
Product Name: | DISC1 Rabbit Polyclonal Antibody |
SKU: | CAB2898 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human DISC1 (NP_001158009.1). |
Sequence: | MPGG GPQG APAA AGGG GVSH RAGS RDCL PPAA CFRR RRLA RRPG YMRS STGP GIGF LSPA VGTL FRFP GGVS GEES HHSE SRAR QCGL DSRG LLVR SPVS KSAA APTV TSVR GTSA HFGI QLRG GTRL PDRL SWPC GPGS AGWQ QEFA AMDS SETL DASW EAAC SDGA RRVR AAGS LPSA ELSS NSCS PGCG PEVP PTPP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SCZD9; C1orf136; DISC1 |
Positive Sample: | U-251MG,293T,SW620,THP-1,mouse pancreas,mouse heart,rat brain,HL-60,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, postsynaptic cell membrane, postsynaptic density, synapse. |
Calculated MW: | 94kDa |
Observed MW: | 105kDa |
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method: | Affinity purification |
Gene ID: | 27185 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |