The DIS3L Polyclonal Antibody (CAB16160) is a valuable tool for researchers studying DIS3L, a protein involved in RNA processing and degradation. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the DIS3L protein, this antibody allows for the detection and analysis of DIS3L levels in various cell types, making it ideal for research in molecular biology and RNA biology.DIS3L is an essential component of the RNA exosome complex, which plays a crucial role in RNA surveillance and degradation. Dysregulation of DIS3L has been associated with various diseases, including cancer and neurodegenerative disorders.
By studying the function of DIS3L and its interactions with other proteins, researchers can gain insight into the mechanisms underlying these diseases and potentially uncover new therapeutic targets.Overall, the DIS3L Polyclonal Antibody is a valuable tool for researchers seeking to explore the role of DIS3L in RNA processing and disease pathogenesis. Its high specificity and sensitivity make it suitable for a wide range of experimental applications, contributing to advancements in our understanding of RNA biology and its implications for human health.
Product Name:
DIS3L Rabbit Polyclonal Antibody
SKU:
CAB16160
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DIS3L (NP_588616.1).
The cytoplasmic RNA exosome complex degrades unstable mRNAs and is involved in the regular turnover of other mRNAs. The protein encoded by this gene contains 3'-5' exoribonuclease activity and is a catalytic component of this complex.
Purification Method:
Affinity purification
Gene ID:
115752
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DIS3L Rabbit pAb (CAB16160) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
