The DIRC1 Polyclonal Antibody (PACO39258) is a valuable tool for researchers studying DIRC1, a crucial protein involved in regulating immune responses. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the DIRC1 protein, this antibody enables researchers to detect and analyze DIRC1 in a variety of cell types, making it an essential tool for studies in immunology and cancer research.
DIRC1, or disrupted in renal carcinoma 1, plays a pivotal role in immune regulation by modulating inflammatory responses and inhibiting allergic reactions. Its involvement in immune function makes it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of DIRC1 is key to developing therapies that can manipulate immune responses in these disease contexts.
Antibody Name:
DIRC1 Antibody (PACO39258)
Antibody SKU:
PACO39258
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Disrupted in renal carcinoma protein 1 protein (1-104AA)
Immunohistochemistry of paraffin-embedded human testis tissue using PACO39258 at dilution of 1:100.
Synonyms:
Disrupted in renal carcinoma protein 1 (Disrupted in renal cancer protein), DIRC1
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
Disruption of DIRC1 by translocation is associated with familial clear cell renal cancer. Overexpression of DIRC1 is associated with tumor progression and poor prognosis in gastric cancer. [provided by RefSeq, Mar 2019]
