The Diras3 Polyclonal Antibody (CAB7950) is a crucial tool for researchers studying the Diras3 protein, which plays a key role in various cellular processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.Diras3, also known as Dual Ras Homolog 3, is involved in signaling pathways that regulate cell proliferation, survival, and differentiation. By targeting the Diras3 protein, researchers can gain insights into its function and impact on different cellular functions.
This antibody enables the detection and analysis of Diras3 in various cell types, making it essential for studies in cell biology, cancer research, and other related fields.The Diras3 Polyclonal Antibody is a valuable tool for researchers aiming to understand the role of Diras3 in normal cellular processes and disease states. By elucidating the function of Diras3, researchers can potentially uncover new therapeutic targets and strategies for treating conditions like cancer and other diseases influenced by Diras3 activity.
Product Name:
DIRAS3 Rabbit Polyclonal Antibody
SKU:
CAB7950
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-229 of human DIRAS3 (NP_004666.1).
This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex.
Purification Method:
Affinity purification
Gene ID:
9077
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DIRAS3 antibody (CAB7950) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
