Based on the information provided in the URL, the DIRAS1 Antibody (PAC02360) is a valuable tool for researchers studying DIRAS1, a small GTPase protein involved in various cellular processes. This antibody is designed for use in Western blot applications and has been validated for its reactivity with human samples.DIRAS1 is known to play a role in cell growth, migration, and proliferation, making it of interest in cancer research and other cellular biology studies. By specifically binding to DIRAS1 protein, this antibody allows for the detection and analysis of DIRAS1 in different cell types, providing insights into its function and potential therapeutic applications.
Overall, the DIRAS1 Antibody offers a valuable resource for researchers looking to further understand the role of DIRAS1 in cellular processes and its potential implications in diseases such as cancer. Its specificity and reliability make it a valuable tool for advancing knowledge in the field of cellular biology and cancer research.
Antibody Name:
DIRAS1 Antibody (PACO22360)
Antibody SKU:
PACO22360
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from C-terminal of human DIRA1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HeLa cells and HepG2 cells, using DIRA1 antibody.
Background:
Displays low GTPase activity and exist predominantly in the GTP-bound form.
Synonyms:
GTP-binding protein Di-Ras1; Distinct subgroup of the Ras family member 1; Ras-related inhibitor of cell growth; Rig protein; Small GTP-binding tumor suppressor 1
UniProt Protein Function:
DIRAS1: Displays low GTPase activity and exist predominantly in the GTP-bound form. Belongs to the small GTPase superfamily. Di-Ras family.Protein type: G protein, monomeric, di-Ras; G protein; G protein, monomericChromosomal Location of Human Ortholog: 19p13.3Cellular Component: plasma membraneMolecular Function: GTP binding; GTPase activity; mitogen-activated protein kinase bindingBiological Process: positive regulation of MAP kinase activity
UniProt Protein Details:
NCBI Summary:
DIRAS1 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.[supplied by OMIM, Apr 2004]
