The DIAPH3 Polyclonal Antibody (CAB10351) is a crucial tool for researchers studying the DIAPH3 protein, which plays a role in cell division and cytoskeletal organization. This antibody, developed through immunization of rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to DIAPH3, it allows for the detection and analysis of this protein in various cell types, making it an excellent choice for studies in cell biology and cancer research.DIAPH3, also known as diaphanous-related formin 3, is involved in regulating actin dynamics and cell migration, making it a key player in processes such as cell division and metastasis.
Understanding the function of DIAPH3 is essential for unraveling its role in cancer progression and other diseases where abnormal cell growth and migration occur. This antibody provides researchers with a valuable tool to investigate the mechanisms of DIAPH3 and explore its potential as a therapeutic target in cancer and other related conditions.
Product Name:
DIAPH3 Rabbit Polyclonal Antibody
SKU:
CAB10351
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 630-849 of human DIAPH3 (NP_112194.2).
This gene encodes a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement and adhesion. Mutations in this gene are associated with autosomal dominant auditory neuropathy 1. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
81624
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DIAPH3 antibody (CAB10351) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
