The DIAPH1 Rabbit Monoclonal Antibody (ABM50320) is a highly specific tool for studying DIAPH1, a protein involved in actin remodeling and cell motility. This antibody, generated in rabbits, shows strong reactivity with human samples and has been validated for use in Western blot applications. By binding to the DIAPH1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for research in cell biology, cancer biology, and developmental biology.
DIAPH1, also known as diaphanous-related formin 1, plays a crucial role in regulating actin dynamics and cell migration. Dysregulation of DIAPH1 has been implicated in various disease processes, including cancer metastasis and developmental disorders. Investigating the function of DIAPH1 with this antibody can provide important insights into the molecular mechanisms underlying these conditions and may lead to the development of novel therapeutic strategies targeting DIAPH1 activity.
Product Name:
DIAPH1 Rabbit Monoclonal Antibody
SKU:
CAB11596
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DIAPH1 (O60610).
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1729
Clone Number:
ARC0639
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of 293T cells, using DIAPH1 Rabbit mAb (CAB11596) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
