DIAPH1 Rabbit Monoclonal Antibody (CAB11596)
- SKU:
- CAB11596
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DIAPH1 Rabbit Monoclonal Antibody |
SKU: | CAB11596 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DIAPH1 (O60610). |
Sequence: | MEPP GGSL GPGR GTRD KKKG RSPD ELPS AGGD GGKS KKFT LKRL MADE LERF TSMR IKKE KEKP NSAH RNSS ASYG DDPT AQSL QDVS DEQV LVLF EQML |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | DIA1; DRF1; DFNA1; LFHL1; SCBMS; hDIA1; mDia1; DIAPH1 |
Positive Sample: | 293T,Mouse lung,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Ruffle membrane, Nucleus |
Calculated MW: | 141kDa |
Observed MW: | 180kDa |
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1729 |
Clone Number: | ARC0639 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |