Smac/Diablo Rabbit Polyclonal Antibody (CAB2564)
- SKU:
- CAB2564
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Smac/Diablo Rabbit Polyclonal Antibody |
SKU: | CAB2564 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 56-239 of human Smac/Diablo (NP_063940.1). |
Sequence: | AVPI AQKS EPHS LSSE ALMR RAVS LVTD STST FLSQ TTYA LIEA ITEY TKAV YTLT SLYR QYTS LLGK MNSE EEDE VWQV IIGA RAEM TSKH QEYL KLET TWMT AVGL SEMA AEAA YQTG ADQA SITA RNHI QLVK LQVE EVHQ LSRK AETK LAEA QIEE LRQK TQEE GEER AESE QEAY LRED |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | SMAC; DFNA64; Smac/Diablo |
Positive Sample: | SW620,BT-474,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 27kDa |
Observed MW: | 18kDa |
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 56616 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |