The DHX58 Polyclonal Antibody (CAB8257) is a valuable tool for studying DHX58, a protein involved in antiviral immunity and RNA metabolism. This antibody, raised in rabbits, has high reactivity with human samples and is validated for use in a variety of applications, including Western blotting. By binding to DHX58, this antibody enables researchers to detect and analyze the protein in different cell types, making it ideal for studies in virology and RNA biology.DHX58, also known as RIG-I-like receptor 1 (RLR-1), plays a crucial role in recognizing viral RNA and initiating immune responses to combat viral infections.
Its involvement in antiviral signaling pathways makes it a key player in the innate immune response and a potential target for drug development in the fight against viral diseases. Research on DHX58 is important for understanding how the immune system detects and responds to viral threats, ultimately leading to the development of novel antiviral strategies.
Product Name:
DHX58 Rabbit Polyclonal Antibody
SKU:
CAB8257
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 389-678 of human DHX58 (NP_077024.2).
Enables double-stranded RNA binding activity; single-stranded RNA binding activity; and zinc ion binding activity. Involved in negative regulation of defense response and negative regulation of type I interferon production. Predicted to be active in cytoplasm.
Purification Method:
Affinity purification
Gene ID:
79132
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using DHX58 Rabbit pAb (CAB8257) at 1:9000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
