The DHX36 Polyclonal Antibody (CAB5191) is a valuable tool for researchers studying DHX36, a protein known for its role in RNA metabolism and immune response regulation. This polyclonal antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.DHX36, also known as RNA helicase DHX36, is involved in numerous biological processes, including RNA processing, splicing, and innate immune response regulation. The DHX36 Polyclonal Antibody binds specifically to the DHX36 protein, allowing for accurate detection and analysis in various cell types.
Research into DHX36 has shown its importance in innate immune response regulation, making it a promising target for studying conditions such as viral infections, autoimmune diseases, and cancer. By understanding the function of DHX36, researchers can uncover new insights into immune system modulation and develop potential therapeutic strategies for a range of diseases.
Product Name:
DHX36 Rabbit Polyclonal Antibody
SKU:
CAB5191
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DHX36 (NP_065916.2).
WB,1:200 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
G4R1; RHAU; DDX36; MLEL1; DHX36
Positive Sample:
Mouse brain,Mouse liver,Mouse kidney,Rat brain
Conjugate:
Unconjugated
Cellular Localization:
Chromosome, Cytoplasm, Nucleus, telomere.
Calculated MW:
115kDa
Observed MW:
114kDa
This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
170506
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using DHX36 Rabbit pAb (CAB5191) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
