The DHX32 Polyclonal Antibody (PAC036862) is a valuable tool for researchers studying DHX32, a protein involved in RNA processing and regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to the DHX32 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and RNA biology.DHX32, also known as RNA helicase, plays a crucial role in regulating gene expression by unwinding RNA molecules and modulating RNA-protein interactions. Its function in RNA metabolism makes it a key player in processes such as mRNA splicing, translation, and degradation.
Research on DHX32 is important for understanding how alterations in RNA processing can contribute to diseases such as cancer, neurodegenerative disorders, and viral infections.By using the DHX32 Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying RNA processing and its impact on cellular functions. This antibody serves as a reliable tool for investigating the role of DHX32 in various biological processes, paving the way for potential therapeutic interventions targeting RNA regulation pathways.
Western Blot. All lanes: DHX32 antibody at 10µg/ml + Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 85, 76 kDa. Observed band size: 85 kDa.
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO36862 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human testis tissue using PACO36862 at dilution of 1:100.
DHX32: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants, but the full length nature of one of the variants has not been defined. [provided by RefSeq, Jul 2008]Protein type: Helicase; EC 3.6.4.13Chromosomal Location of Human Ortholog: 10q26.2Cellular Component: cytoplasm; spliceosomeMolecular Function: ATP-dependent RNA helicase activity; protein bindingBiological Process: nuclear mRNA splicing, via spliceosome
UniProt Protein Details:
NCBI Summary:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants, but the full length nature of one of the variants has not been defined. [provided by RefSeq, Jul 2008]
