The DHX30 Polyclonal Antibody (CAB8575) is a valuable tool for researchers studying the DHX30 protein, a key player in RNA metabolism and RNA virus infection. This antibody is produced in rabbits and has been validated for its specificity in Western blot applications, allowing for accurate detection and analysis of DHX30 protein levels in various cell types.DHX30, a member of the DEAH-box RNA helicase family, is involved in RNA processing and plays a crucial role in innate immune responses to viral infections. By targeting DHX30 with this antibody, researchers can gain insights into the mechanisms underlying RNA virus infection and potentially identify novel therapeutic targets for antiviral strategies.
With its high reactivity with human samples and proven efficacy in Western blotting, the DHX30 Polyclonal Antibody is a valuable tool for studying RNA metabolism, virus-host interactions, and immune responses. Its application in virology, immunology, and molecular biology research makes it an essential component of any laboratory focused on understanding the complexities of RNA biology and viral infections.
Product Name:
DHX30 Rabbit Polyclonal Antibody
SKU:
CAB8575
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 906-1155 of human DHX30 (NP_055781.2).
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The family member encoded by this gene is a mitochondrial nucleoid protein that associates with mitochondrial DNA. It has also been identified as a component of a transcriptional repressor complex that functions in retinal development, and it is required to optimize the function of the zinc-finger antiviral protein. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
22907
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DHX30 antibody (CAB8575) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
