The DHX16 Polyclonal Antibody (PACO08830) is ideal for researchers studying the DHX16 protein, a member of the DEAH-box RNA helicase family involved in RNA metabolism and cellular processes. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in various applications, including Western blotting.DHX16 is known for its role in RNA processing, playing a critical role in gene expression and RNA splicing. Its function in regulating RNA molecules makes it a key player in developmental processes and disease pathways. By targeting DHX16 with this antibody, researchers can better understand its involvement in cellular functions and potentially uncover new therapeutic targets in diseases like cancer and neurodegenerative disorders.
The DHX16 Polyclonal Antibody is a valuable tool for investigating the functions of DHX16 in various cellular contexts, providing insights into RNA metabolism and potential therapeutic opportunities. Its high reactivity and specificity make it a reliable choice for studies in molecular biology, genetics, and RNA biology. Unlock the mysteries of DHX16 with this versatile antibody for your research needs.
DDX16: a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. Probable ATP-binding RNA helicase involved in pre-mRNA splicing. Protein type: EC 3.6.4.13; Helicase; RNA processing; RNA-binding; SpliceosomeChromosomal Location of Human Ortholog: 6p21.33Cellular Component: cytoplasm; nucleoplasm; nucleus; spliceosomal complexMolecular Function: ATP binding; ATP-dependent RNA helicase activity; ATPase activity; protein binding; RNA binding; RNA helicase activityBiological Process: mRNA splicing, via spliceosome; RNA splicing
UniProt Protein Details:
NCBI Summary:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
