The DHX15 Polyclonal Antibody (PACO56780) is a valuable tool for researchers studying DHX15, a helicase protein involved in RNA metabolism and gene expression regulation. This antibody, produced in rabbits, is highly specific for DHX15 in human samples and has been validated for use in Western blot applications. By binding to DHX15, it enables accurate detection and analysis of this important protein in a variety of cell types, making it ideal for studies in molecular biology and RNA metabolism research.DHX15 is known for its role in unwinding RNA structures and facilitating various RNA-dependent processes, including splicing and translation.
Its functions in gene expression regulation make it a key player in cellular metabolism and development. Research on DHX15 can provide insights into how disruptions in RNA metabolism contribute to diseases like cancer, neurological disorders, and viral infections. By understanding the mechanisms of DHX15, researchers can potentially uncover new therapeutic targets for these conditions.
Antibody Name:
DHX15 Antibody (PACO56780)
Antibody SKU:
PACO56780
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Human
Immunogen:
Recombinant Human Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 protein (371-502AA)
Western Blot. Positive WB detected in: 293 whole cell lysate. All lanes: DHX15 antibody at 3.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 91 kDa. Observed band size: 91 kDa.
Background:
Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns.
