The DHTKD1 Polyclonal Antibody (CAB8369) is a valuable tool for researchers studying the DHTKD1 protein, which is involved in lysine metabolism and plays a crucial role in the production of alpha-ketoglutarate. This antibody, raised in rabbits, has high reactivity with human samples and is validated for use in Western blot applications.The DHTKD1 antibody specifically binds to the DHTKD1 protein, allowing for precise detection and analysis in a variety of cell types. This makes it ideal for studies in metabolism, biochemistry, and mitochondrial function research. The DHTKD1 protein is essential for maintaining proper lysine metabolism and energy production in cells, making it a key target for understanding metabolic disorders and mitochondrial dysfunction.
By using the DHTKD1 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of the DHTKD1 protein, potentially leading to advancements in the treatment of metabolic disorders, mitochondrial diseases, and other related conditions. Understanding the role of DHTKD1 in cellular metabolism is crucial for developing targeted therapies and interventions for individuals with metabolic disorders.
Product Name:
DHTKD1 Rabbit Polyclonal Antibody
SKU:
CAB8369
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human DHTKD1 (NP_061176.3).
This gene encodes a component of a mitochondrial 2-oxoglutarate-dehydrogenase-complex-like protein involved in the degradation pathways of several amino acids, including lysine. Mutations in this gene are associated with 2-aminoadipic 2-oxoadipic aciduria and Charcot-Marie-Tooth Disease Type 2Q.
Purification Method:
Affinity purification
Gene ID:
55526
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using DHTKD1 Rabbit pAb (CAB8369) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
