The DHRS9 Polyclonal Antibody (CAB6324) is a valuable tool for researchers studying the DHRS9 protein, which plays a key role in cellular metabolism and lipid synthesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the DHRS9 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in metabolism, lipid biology, and related research areas.DHRS9, also known as dehydrogenase reductase SDR family member 9, is involved in the conversion of aldehydes to alcohols and plays a crucial role in maintaining cellular homeostasis.
Dysregulation of DHRS9 has been linked to various metabolic disorders, making it a potential therapeutic target for conditions such as obesity, diabetes, and cardiovascular diseases. Understanding the function of DHRS9 is essential for developing targeted treatments that can modulate lipid metabolism and improve metabolic health.Overall, the DHRS9 Polyclonal Antibody (CAB6324) offers researchers a reliable tool for investigating the role of DHRS9 in cellular metabolism and lipid synthesis, paving the way for advancements in the treatment and prevention of metabolic disorders.
Product Name:
DHRS9 Rabbit Polyclonal Antibody
SKU:
CAB6324
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 18-319 of human DHRS9 (NP_001135743.1).
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10170
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DHRS9 antibody (CAB6324) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (AbGn00020)._Exposure time: 390s.
