DHRS12 Antibody (PACO26233)
- SKU:
- PACO26233
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
DHRS12 Antibody (PACO26233)
The DHRS12 Polyclonal Antibody (PACO26233) is a valuable tool for researchers studying DHRS12, a member of the short-chain dehydrogenase/reductase (SDR) family involved in lipid metabolism and retinoic acid signaling. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.DHRS12 plays a crucial role in cellular processes such as fatty acid metabolism, cholesterol biosynthesis, and retinoid metabolism.
Its involvement in these pathways makes it a potential target for therapeutic interventions in conditions such as metabolic disorders, cardiovascular disease, and cancer. The DHRS12 Polyclonal Antibody allows for the detection and analysis of DHRS12 protein expression in various cell types, aiding researchers in further understanding its function and potential implications in human health.
| Antibody Name: | DHRS12 Antibody (PACO26233) |
| Antibody SKU: | PACO26233 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Dehydrogenase/reductase SDR family member 12 protein (1-271AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: DHRS12 antibody at 1.3µg/ml + Human placenta tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 36, 28, 31 kDa Observed band size: 31 kDa . |
 | Immunohistochemistry of paraffin-embedded human cervical cancer using PACO26233 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO26233 at dilution of 1:100. |
| Background: | Putative oxidoreductase. |
| Synonyms: | Dehydrogenase/reductase SDR family member 12 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 40C member 1), DHRS12, SDR40C1 |
| UniProt Protein Function: | DHRS12: Putative oxidoreductase. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: EC 1.1.-.-; OxidoreductaseChromosomal Location of Human Ortholog: 13q14.3Molecular Function: oxidoreductase activity |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family, which has over 46,000 members. Members in this family are enzymes that metabolize many different compounds, such as steroid hormones, prostaglandins, retinoids, lipids and xenobiotics. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012] |
| UniProt Code: | A0PJE2 |
| NCBI GenInfo Identifier: | 72534732 |
| NCBI Gene ID: | 79758 |
| NCBI Accession: | NP_001026889.1 |
| UniProt Secondary Accession: | A0PJE2,Q96GB2, Q9H8H1 |
| UniProt Related Accession: | A0PJE2 |
| Molecular Weight: | 30,850 Da |
| NCBI Full Name: | dehydrogenase/reductase SDR family member 12 isoform 1 |
| NCBI Synonym Full Names: | dehydrogenase/reductase (SDR family) member 12 |
| NCBI Official Symbol: | DHRS12Â Â |
| NCBI Official Synonym Symbols: | SDR40C1Â Â |
| NCBI Protein Information: | dehydrogenase/reductase SDR family member 12 |
| UniProt Protein Name: | Dehydrogenase/reductase SDR family member 12 |
| UniProt Synonym Protein Names: | Short-chain dehydrogenase/reductase family 40C member 1 |
| Protein Family: | Dehydrogenase/reductase SDR family |
| UniProt Gene Name: | DHRS12Â Â |
| UniProt Entry Name: | DHR12_HUMAN |
Related Products
