The DHRs11 Polyclonal Antibody (CAB14422) is a valuable tool for researchers studying DHRs11, a key player in oxidative stress response pathways. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting DHRs11 in human samples, making it ideal for applications such as Western blot. By binding to the DHRs11 protein, this antibody enables researchers to monitor and analyze its expression levels in various cell types, facilitating investigations in fields like oxidative stress, inflammation, and aging research.
DHRs11, also known as a member of the dual oxidase family, plays a crucial role in generating reactive oxygen species (ROS) and maintaining redox balance within cells. Dysregulation of DHRs11 has been implicated in various pathological conditions, including cardiovascular diseases, neurodegenerative disorders, and cancer. By elucidating the function of DHRs11, researchers can uncover potential therapeutic targets for combating oxidative stress-related diseases and developing novel treatment strategies.
Product Name:
DHRS11 Rabbit Polyclonal Antibody
SKU:
CAB14422
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DHRS11 (NP_077284.2).
Enables 17-beta-hydroxysteroid dehydrogenase (NADP+) activity; 17-beta-ketosteroid reductase activity; and 3-keto sterol reductase activity. Involved in steroid biosynthetic process. Predicted to be located in extracellular region.
Purification Method:
Affinity purification
Gene ID:
79154
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DHRS11 Rabbit pAb (CAB14422) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
