DHH Rabbit Polyclonal Antibody (CAB13177)
- SKU:
- CAB13177
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | DHH Rabbit Polyclonal Antibody |
SKU: | CAB13177 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 199-396 of human DHH (NP_066382.1). |
Sequence: | CFPG NATV RLWS GERK GLRE LHRG DWVL AADA SGRV VPTP VLLF LDRD LQRR ASFV AVET EWPP RKLL LTPW HLVF AARG PAPA PGDF APVF ARRL RAGD SVLA PGGD ALRP ARVA RVAR EEAV GVFA PLTA HGTL LVND VLAS CYAV LESH QWAH RAFA PLRL LHAL GALL PGGA VQPT GMHW YSRL LYRL AEEL LG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GDMN; GDXYM; HHG-3; SRXY7; DHH |
Positive Sample: | Mouse skeletal muscle,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Extracellular side, Lipid-anchor, Secreted, extracellular space. |
Calculated MW: | 44kDa |
Observed MW: | 44kDa |
This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.
Purification Method: | Affinity purification |
Gene ID: | 50846 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |