DGUOK Rabbit Polyclonal Antibody (CAB6898)
- SKU:
- CAB6898
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DGUOK Rabbit Polyclonal Antibody |
SKU: | CAB6898 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-277 of human DGUOK (NP_550438.1). |
Sequence: | RLSI EGNI AVGK STFV KLLT KTYP EWHV ATEP VATW QNIQ AAGT QKAC TAQS LGNL LDMM YREP ARWS YTFQ TFSF LSRL KVQL EPFP EKLL QARK PVQI FERS VYSD RYIF AKNL FENG SLSD IEWH IYQD WHSF LLWE FASR ITLH GFIY LQAS PQVC LKRL YQRA REEE KGIE LAYL EQLH GQHE AWLI HKTT KLHF EALM NIPV LVLD VNDD FSEE VTKQ EDLM REVN TFVK NL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | dGK; NCPH; NCPH1; PEOB4; MTDPS3; DGUOK |
Positive Sample: | Jurkat,HepG2,Mouse heart,Mouse kidney,Rat liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 32kDa |
Observed MW: | 40kDa |
In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1716 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |