The DGKZ Polyclonal Antibody (CAB16457) is a powerful tool for researchers studying DGKZ, a key enzyme involved in lipid signaling pathways. This antibody, generated in rabbits, exhibits high specificity towards human samples and has been rigorously validated for use in Western blotting applications. By targeting the DGKZ protein, this antibody enables precise detection and analysis in a variety of cell types, making it an invaluable asset for investigations in cell signaling, lipid metabolism, and cancer biology.
DGKZ, or diacylglycerol kinase zeta, plays a crucial role in regulating cellular functions by modulating levels of diacylglycerol and phosphatidic acid, lipid molecules with diverse signaling roles. Dysregulation of DGKZ has been implicated in various diseases, including cancer, neurological disorders, and immune dysfunction. By understanding the role of DGKZ in these contexts, researchers can uncover potential therapeutic targets for the development of novel treatments.
Product Name:
DGKZ Rabbit Polyclonal Antibody
SKU:
CAB16457
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 808-1117 of human DGKZ (NP_001099010.1).
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
8525
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DGKZ Rabbit pAb (CAB16457) at 1:300 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
