The DGKK Polyclonal Antibody (PACO03500) is a valuable tool for researchers studying DGKK, a key protein involved in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity and specificity towards DGKK in human samples, making it ideal for use in Western blot applications. By binding to DGKK, this antibody enables precise detection and analysis of the protein in different cell types, allowing for in-depth investigations in fields such as cell biology, signal transduction, and disease mechanisms.DGKK, also known as diacylglycerol kinase kappa, is a crucial enzyme that plays a role in lipid signaling pathways and intracellular membrane trafficking. Its functions are diverse and impact processes like cell growth, differentiation, and cell death regulation.
Research on DGKK has implications in various areas, including cancer biology, neurobiology, and lipid metabolism. Understanding the functions and regulation of DGKK is essential for unveiling its potential as a therapeutic target in diseases related to lipid dysregulation and cellular signaling pathways.Overall, the DGKK Polyclonal Antibody (PACO03500) serves as a reliable tool for researchers aiming to explore the function and regulation of DGKK in different biological contexts. Its high specificity and sensitivity make it a valuable asset for studies seeking to uncover the intricate roles of DGKK in health and disease.
Antibody Name:
DGKK Antibody
Antibody SKU:
PACO03500
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC, IF
Recommended Dilutions:
IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human DGK-Kappa.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
DGKK: Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Belongs to the eukaryotic diacylglycerol kinase family.Protein type: EC 2.7.1.107; Kinase, lipidChromosomal Location of Human Ortholog: Xp11.22Cellular Component: cytoplasm; plasma membraneMolecular Function: ATP binding; diacylglycerol kinase activity; metal ion bindingBiological Process: blood coagulation; diacylglycerol metabolic process; phosphorylation; platelet activation; protein kinase C activation; response to oxidative stress
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011]
