DGKI Antibody (PACO00701)
- SKU:
- PACO00701
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
DGKI Antibody (PACO00701)
The DGKI Polyclonal Antibody (PACO00701) is a valuable tool for researchers studying the role of diacylglycerol kinase iota (DGKI) in various biological processes. DGKI is a key enzyme involved in lipid signaling pathways, particularly in the regulation of intracellular diacylglycerol levels. This antibody, raised in rabbits, exhibits high specificity and sensitivity towards DGKI in human samples, making it suitable for Western blot applications.DGKI has been implicated in a wide range of physiological functions, including cell proliferation, differentiation, and neuronal development. Dysregulation of DGKI has been linked to various diseases, such as cancer, neurodegenerative disorders, and metabolic conditions.
By targeting DGKI with this antibody, researchers can gain insights into its role in these disease processes and potentially identify novel therapeutic targets for intervention.With its ability to detect DGKI in different cell types and tissues, this antibody is an essential tool for investigating the diverse functions of DGKI in both normal and pathological conditions. Its reliability and accuracy make it a valuable asset for studies in molecular biology, cell signaling, and disease mechanisms. Unlock the potential of DGKI research with the PACO00701 antibody from AssayGenie.
| Antibody Name: | DGKI Antibody |
| Antibody SKU: | PACO00701 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Rat |
| Immunogen: | synthesized peptide derived from the C-terminal region of human DGK-?. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | DGKI; Diacylglycerol kinase iota; DAG kinase iota; Diglyceride kinase iota; DGK-iota |
| UniProt Protein Function: | DGKI: a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Kinase, lipid; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - glycerolipid; Motility/polarity/chemotaxis; EC 2.7.1.107 Chromosomal Location of Human Ortholog: 7q32.3-q33 Cellular Component: cytoplasm; dendritic spine; nucleoplasm; nucleus; plasma membrane; protein complex; synapse Molecular Function:diacylglycerol kinase activity; protein binding Biological Process: platelet activation |
| NCBI Summary: | This gene is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75912 |
| NCBI GenInfo Identifier: | 12643642 |
| NCBI Gene ID: | 9162 |
| NCBI Accession: | O75912.1 |
| UniProt Secondary Accession: | O75912,Q9NZ49, A4D1Q9, |
| UniProt Related Accession: | O75912 |
| Molecular Weight: | 116,997 Da |
| NCBI Full Name: | Diacylglycerol kinase iota |
| NCBI Synonym Full Names: | diacylglycerol kinase iota |
| NCBI Official Symbol: | DGKIÂ Â |
| NCBI Official Synonym Symbols: | DGK-IOTAÂ Â |
| NCBI Protein Information: | diacylglycerol kinase iota |
| UniProt Protein Name: | Diacylglycerol kinase iota |
| UniProt Synonym Protein Names: | Diglyceride kinase iota; DGK-iota |
| Protein Family: | Diacylglycerol kinase |
| UniProt Gene Name: | DGKIÂ Â |
| UniProt Entry Name: | DGKI_HUMAN |
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