The DGKA Monoclonal Antibody (CAB22127) is a specialized tool for researchers studying DGKA, a protein involved in various cellular processes including lipid metabolism and signaling pathways. This monoclonal antibody, developed using cutting-edge technology, specifically targets DGKA in human samples and is validated for use in various experimental applications such as immunofluorescence and flow cytometry.DGKA, also known as diacylglycerol kinase alpha, plays a crucial role in regulating lipid signaling and has been implicated in diseases such as cancer and neurodegenerative disorders.
By targeting DGKA with this monoclonal antibody, researchers can gain insights into the function and localization of the protein within cells, providing valuable information for studies in molecular biology and drug development.Overall, the DGKA Monoclonal Antibody (CAB22127) offers a powerful tool for investigating the role of DGKA in health and disease, paving the way for new discoveries and potential therapeutic interventions.
Product Name:
DGKA Monoclonal Antibody
SKU:
CAB22127
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human DGKA (NP_001336.2).
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Several transcript variants encoding different isoforms have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
1606
Clone Number:
ARC55777
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using DGKA antibody (CAB22127) at1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
