DGCR8 Rabbit Polyclonal Antibody (CAB18630)
- SKU:
- CAB18630
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DGCR8 Rabbit Polyclonal Antibody |
SKU: | CAB18630 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-340 of human DGCR8 (NP_073557.3). |
Sequence: | DKKD EENE LDQE KRVE YAVL DELE DFTD NLEL DEEG AGGF TAKA IVQR DRVD EEAL NFPY EDDF DNDV DALL EEGL CAPK KRRT EEKY GGDS DHPS DGET SVQP MMTK IKTV LKSR GRPP TEPL PDGW IMTF HNSG VPVY LHRE SRVV TWSR PYFL GTGS I |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | Gy1; pasha; DGCRK6; C22orf12; DGCR8 |
Positive Sample: | HepG2,HeLa,293T,Mouse testis |
Cellular Localization: | Nucleus, nucleolus. |
Calculated MW: | 86kDa |
Observed MW: | 110kDa |
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 54487 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |