The DGAT2L6 Polyclonal Antibody (PACO04122) is a valuable tool for researchers studying the DGAT2L6 protein, an enzyme involved in lipid metabolism and potentially linked to obesity and metabolic diseases. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards DGAT2L6 in human samples, making it suitable for Western blot applications.DGAT2L6, a member of the diacylglycerol O-acyltransferase (DGAT) enzyme family, plays a crucial role in triglyceride synthesis and lipid storage. Dysregulation of DGAT2L6 expression and activity has been implicated in metabolic disorders and may serve as a therapeutic target for diseases such as obesity, diabetes, and cardiovascular diseases.
By utilizing the DGAT2L6 Polyclonal Antibody, researchers can study the expression levels and localization of DGAT2L6 in various cell types and tissues, providing insight into its function and potential implications in metabolic diseases. This antibody is a valuable tool for advancing our understanding of lipid metabolism and developing targeted therapies for related disorders.
Antibody Name:
DGAT2L6 Antibody
Antibody SKU:
PACO04122
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human DGAT2L6.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
DGAT2L6: Probable acyltransferase uses fatty acyl-CoA as substrate. Has no wax synthase activity to produce wax esters. Belongs to the diacylglycerol acyltransferase family.Protein type: EC 2.3.1.-; Membrane protein, multi-pass; Transferase; Membrane protein, integralChromosomal Location of Human Ortholog: Xq13.1Cellular Component: endoplasmic reticulum membrane; integral to membraneMolecular Function: transferase activity, transferring groups other than amino-acyl groupsBiological Process: lipid metabolic process
UniProt Protein Details:
NCBI Summary:
This gene is a member of the diacylglycerol acyltransferase 2 family. The encoded protein is a putative acyltransferase and is most likely involved in the synthesis of di- or triacylglycerol, however its substrate specificity is currently unknown. [provided by RefSeq, Feb 2015]
