The DGAT2 Polyclonal Antibody (CAB13891) is a valuable tool for researchers studying diacylglycerol O-acyltransferase 2 (DGAT2), an enzyme involved in triglyceride synthesis and lipid metabolism. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the DGAT2 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential tool for studies in cell biology and lipid metabolism research.DGAT2 is a key enzyme in the synthesis of triglycerides, playing a crucial role in lipid homeostasis and energy storage.
Dysregulation of DGAT2 has been implicated in various metabolic disorders, making it a potential target for therapeutic interventions aimed at controlling lipid metabolism and treating conditions such as obesity, diabetes, and cardiovascular diseases. Investigating the function of DGAT2 with this antibody can provide valuable insights into lipid metabolism pathways and potential therapeutic strategies for metabolic disorders.
Product Name:
DGAT2 Rabbit Polyclonal Antibody
SKU:
CAB13891
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 289-388 of human DGAT2 (NP_115953.2).
This gene encodes one of two enzymes which catalyzes the final reaction in the synthesis of triglycerides in which diacylglycerol is covalently bound to long chain fatty acyl-CoAs. The encoded protein catalyzes this reaction at low concentrations of magnesium chloride while the other enzyme has high activity at high concentrations of magnesium chloride. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
84649
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat liver , using DGAT2 Rabbit pAb (CAB13891) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (AbGn00020)._Exposure time: 60s.
