The DGAT1 Polyclonal Antibody (CAB6857) is a valuable tool for research involving DGAT1, an enzyme that plays a key role in lipid metabolism and energy balance. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the DGAT1 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for studies in metabolic disorders, obesity, and lipid biology research.DGAT1, also known as diacylglycerol O-acyltransferase 1, is involved in the synthesis of triglycerides, which are essential for storing and transporting energy in the body.
Dysregulation of DGAT1 activity has been linked to metabolic disorders such as obesity, diabetes, and cardiovascular diseases. By studying the function of DGAT1, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment.Overall, the DGAT1 Polyclonal Antibody offers researchers a reliable tool for investigating the role of DGAT1 in lipid metabolism and its implications for metabolic diseases. Its high specificity and sensitivity make it a valuable asset for advancing our understanding of lipid homeostasis and developing targeted therapies for related health conditions.
Product Name:
DGAT1 Rabbit Polyclonal Antibody
SKU:
CAB6857
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 201-300 of human DGAT1 (NP_036211.2).
This gene encodes an multipass transmembrane protein that functions as a key metabolic enzyme. The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol. This enzyme can also transfer acyl CoA to retinol. Activity of this protein may be associated with obesity and other metabolic diseases.
Purification Method:
Affinity purification
Gene ID:
8694
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using DGAT1 Rabbit pAb (CAB6857) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
