The DGAT1 Monoclonal Antibody (CAB23078) is a valuable tool for researchers studying diacylglycerol O-acyltransferase 1 (DGAT1), a key enzyme involved in lipid metabolism and energy storage. This antibody, produced through hybridoma technology, exhibits high specificity and sensitivity towards DGAT1 in various experimental settings, such as immunofluorescence and flow cytometry.DGAT1 is known for its pivotal role in the synthesis of triglycerides, which are essential components of cellular membranes and energy storage molecules. Dysregulation of DGAT1 has been linked to metabolic disorders, such as obesity and insulin resistance, making it a promising target for therapeutic interventions aimed at managing lipid-related diseases.
By utilizing the DGAT1 Monoclonal Antibody, researchers can effectively probe the expression and localization of DGAT1 in different cell types and tissues, shedding light on its functional significance in physiological and pathological conditions. This antibody holds great potential for advancing our understanding of lipid metabolism and developing novel therapeutic strategies for metabolic disorders.
This gene encodes an multipass transmembrane protein that functions as a key metabolic enzyme. The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol. This enzyme can also transfer acyl CoA to retinol. Activity of this protein may be associated with obesity and other metabolic diseases.
Purification Method:
Affinity purification
Gene ID:
8694
Clone Number:
ARC58696
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human liver using DGAT1 Rabbit mAb (CAB23078) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
