The DGAT1 Monoclonal Antibody (CAB23077) is a valuable tool for researchers studying diacylglycerol O-acyltransferase 1 (DGAT1), an enzyme involved in lipid metabolism and lipid droplet formation. This monoclonal antibody, derived from mouse hybridoma cells, exhibits high specificity and sensitivity for detecting DGAT1 protein in various experimental settings, such as Western blot analysis.DGAT1 plays a crucial role in the synthesis of triglycerides and is implicated in diseases like obesity, diabetes, and metabolic disorders. By targeting DGAT1 with this antibody, researchers can investigate its functions in lipid metabolism, energy balance, and lipid-related diseases.
The ability to detect DGAT1 protein levels and localization in cells provides insight into its cellular functions and potential as a therapeutic target in metabolic disorders.With its high reactivity in human samples, the DGAT1 Monoclonal Antibody is a valuable tool for advancing research in lipid biology, metabolic diseases, and drug development. Researchers can utilize this antibody to explore the role of DGAT1 in various cellular processes, paving the way for new discoveries and potential treatment strategies for metabolic disorders.
This gene encodes an multipass transmembrane protein that functions as a key metabolic enzyme. The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol. This enzyme can also transfer acyl CoA to retinol. Activity of this protein may be associated with obesity and other metabolic diseases.
Purification Method:
Affinity purification
Gene ID:
8694
Clone Number:
ARC58697
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using DGAT1 antibody (CAB23077) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
