Desmoplakin Rabbit Polyclonal Antibody (CAB7635)
- SKU:
- CAB7635
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Desmoplakin Rabbit Polyclonal Antibody |
SKU: | CAB7635 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Desmoplakin (NP_004406.2). |
Sequence: | MSCN GGSH PRIN TLGR MIRA ESGP DLRY EVTS GGGG TSRM YYSR RGVI TDQN SDGY CQTG TMSR HQNQ NTIQ ELLQ NCSD CLMR AELI VQPE LKYG DGIQ |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | DP; DCWHKTA; Desmoplakin |
Positive Sample: | A-431,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cytoplasm, cytoskeleton, desmosome. |
Calculated MW: | 332kDa |
Observed MW: | 330kDa |
This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1832 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |