Desmoglein 3 Rabbit Monoclonal Antibody (CAB5227)
- SKU:
- CAB5227
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Desmoglein 3 Rabbit Monoclonal Antibody |
SKU: | CAB5227 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 900-999 of human Desmoglein 3 (P32926). |
Sequence: | TLSG SQGA SALS TSGS VQPA VSIP DPLQ HGNY LVTE TYSA SGSL VQPS TAGF DPLL TQNV IVTE RVIC PISS VPGN LAGP TQLR GSHT MLCT EDPC SRLI |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | PVA; ABOLM; CDHF6; Desmoglein 3 |
Positive Sample: | A-431,Cal-27 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome. |
Calculated MW: | 108kDa |
Observed MW: | 145kDa |
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.
Purification Method: | Affinity purification |
Gene ID: | 1830 |
Clone Number: | ARC1190 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |