Desmoglein 3 Rabbit Polyclonal Antibody (CAB8412)
- SKU:
- CAB8412
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Desmoglein 3 Rabbit Polyclonal Antibody |
SKU: | CAB8412 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 749-999 of human Desmoglein 3 (NP_001935.2). |
Sequence: | FGAA TGVG ICSS GQSG TMRT RHST GGTN KDYA DGAI SMNF LDSY FSQK AFAC AEED DGQE ANDC LLIY DNEG ADAT GSPV GSVG CCSF IADD LDDS FLDS LGPK FKKL AEIS LGVD GEGK EVQP PSKD SGYG IESC GHPI EVQQ TGFV KCQT LSGS QGAS ALST SGSV QPAV SIPD PLQH GNYL VTET YSAS GSLV QPST AGFD PLLT QNVI VTER VICP ISSV PGNL AGPT QLRG SHTM LCTE DPCS RLI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | PVA; ABOLM; CDHF6; Desmoglein 3 |
Positive Sample: | A431 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome. |
Calculated MW: | 108kDa |
Observed MW: | 130kDa |
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.
Purification Method: | Affinity purification |
Gene ID: | 1830 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |