DSC2 Rabbit Polyclonal Antibody (CAB10211)
- SKU:
- CAB10211
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DSC2 Rabbit Polyclonal Antibody |
SKU: | CAB10211 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-690 of human DSC2 (NP_077740.1). |
Sequence: | IDEN TGSI KVFR SLDR EAET IKNG IYNI TVLA SDQG GRTC TGTL GIIL QDVN DNSP FIPK KTVI ICKP TMSS AEIV AVDP DEPI HGPP FDFS LESS TSEV QRMW RLKA INDT AARL SYQN DPPF GSYV VPIT VRDR LGMS SVTS LDVT LCDC ITEN DCTH RVDP RIGG GGV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | DG2; DSC3; CDHF2; ARVD11; DGII/III; DSC2 |
Positive Sample: | A-431,Raji,LO2,BT-474,HT-29 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome. |
Calculated MW: | 100kDa |
Observed MW: | 100kDa |
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1824 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |