The Desmin Rabbit Monoclonal Antibody (CAB3736) is a vital tool for researchers studying desmin, a protein essential for the structure and function of muscle cells. This antibody, produced in rabbits, is highly specific to desmin in human samples and is validated for use in various applications such as immunohistochemistry and western blotting.Desmin is a key component of the intermediate filaments in muscle cells, providing structural support and helping to maintain the organization of the sarcomeres. Dysregulation of desmin expression or mutation of the desmin gene has been implicated in various muscle disorders, making it a crucial target for research in muscle biology and diseases.
This Desmin Rabbit Monoclonal Antibody allows for accurate detection and analysis of desmin in different cell types and tissues, providing valuable insights into its function and role in muscle physiology. Researchers in the fields of muscle biology, cardiology, and neuromuscular diseases will find this antibody indispensable for their studies on desmin and related pathways.
Product Name:
Desmin Rabbit Monoclonal Antibody
SKU:
CAB3736
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 371-470 of human Desmin (P17661).
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Purification Method:
Affinity purification
Gene ID:
1674
Clone Number:
ARC0235
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Desmin Rabbit mAb (CAB3736) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
