The Desmin Polyclonal Antibody (CAB10838) is a valuable tool for researchers studying Desmin, a protein that plays a crucial role in maintaining the structural integrity of muscle cells. This antibody, generated in rabbits, is highly specific to human Desmin and has been validated for use in Western blot applications.Desmin is a type III intermediate filament protein found in muscle cells, where it provides support and stability to the cell structure. Dysregulation of Desmin has been linked to various muscle-related disorders, making it an important target for research in the fields of muscular dystrophy, heart disease, and muscle injury.
By using the Desmin Polyclonal Antibody, researchers can accurately detect and analyze Desmin expression in different cell types and tissues, providing insights into its role in muscle function and disease pathology. This antibody is a valuable tool for advancing our understanding of Desmin biology and its implications for human health.
Product Name:
Desmin Rabbit Polyclonal Antibody
SKU:
CAB10838
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 121-470 of human Desminmin (NP_001918.3).
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Purification Method:
Affinity purification
Gene ID:
1674
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using Desmin Rabbit pAb (CAB10838).
