The DEPDC1B Polyclonal Antibody (PACO53154) is a valuable tool for researchers studying DEPDC1B, a protein involved in cell cycle regulation and tumor development. This antibody, generated in rabbits, shows high specificity and sensitivity in detecting DEPDC1B in human samples, making it an ideal choice for immunohistochemistry and Western blot applications.DEPDC1B, a member of the DEP domain-containing protein family, is known to play a role in cell proliferation and cancer progression.
Its overexpression has been linked to various types of cancer, making it a potential target for cancer therapy research. By using the DEPDC1B Polyclonal Antibody, researchers can accurately assess DEPDC1B levels in different cell types and tissues, leading to a better understanding of its function and potential implications in cancer biology.
Western Blot. Positive WB detected in: HEK293 whole cell lysate. All lanes: DEPDC1B antibody at 4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 62, 55 kDa. Observed band size: 62 kDa.
Immunohistochemistry of paraffin-embedded human liver cancer using PACO53154 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human testis tissue using PACO53154 at dilution of 1:100.
Background:
cytosol, GTPase activator activity, cell migration, positive regulation of Wnt signaling pathway, regulation of small GTPase mediated signal transduction
Synonyms:
DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8), DEPDC1B, XTP8
UniProt Protein Function:
DEPDC1B: 2 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs; GAPs, Rac/RhoChromosomal Location of Human Ortholog: 5q12.1Cellular Component: cytosolMolecular Function: GTPase activator activityBiological Process: cell migration; positive regulation of GTPase activity; positive regulation of Wnt receptor signaling pathway; regulation of small GTPase mediated signal transduction
