The DEPDC1 Polyclonal Antibody (PACO16176) is a valuable tool for researching DEPDC1, a protein associated with cell growth and proliferation. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By targeting the DEPDC1 protein, researchers can study its role in various cellular processes, making it an essential tool for investigations in cancer biology and developmental biology.
DEPDC1, also known as DEP domain-containing protein 1, is implicated in regulating cell division and growth, making it a potential target for cancer therapies. Understanding the function of DEPDC1 is critical in unraveling the mechanisms of tumorigenesis and identifying novel therapeutic strategies. The DEPDC1 Polyclonal Antibody provides researchers with a reliable tool to investigate the role of DEPDC1 in cancer progression and development.
Antibody Name:
DEPDC1 Antibody (PACO16176)
Antibody SKU:
PACO16176
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:1000-1:2000, WB:1:200-1:1000
Species Reactivity:
Human
Immunogen:
Fusion protein of human DEPDC1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-4: A172 cells, hela cells, hepg2 cells, 293T cells, Primary antibody: PACO16176(DEPDC1 Antibody) at dilution 1/150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute.
Background:
DEP domain containing 1 is a protein in humans that is encoded by the DEPDC1 gene. May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
