Delta-sarcoglycan (SGCD) Rabbit Polyclonal Antibody (CAB6980)
- SKU:
- CAB6980
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Delta-sarcoglycan (SGCD) Rabbit Polyclonal Antibody |
SKU: | CAB6980 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 61-290 of human Delta-sarcoglycan (Delta-sarcoglycan (SGCD)) (NP_000328.2). |
Sequence: | NFTI DGMG NLRI TEKG LKLE GDSE FLQP LYAK EIQS RPGN ALYF KSAR NVTV NILN DQTK VLTQ LITG PKAV EAYG KKFE VKTV SGKL LFSA DNNE VVVG AERL RVLG AEGT VFPK SIET PNVR ADPF KELR LESP TRSL VMEA PKGV EINA EAGN MEAT CRTE LRLE SKDG EIKL DAAK IRLP RLPH GSYT PTGT RQKV FEIC VCAN GRLF LSQA GAGS TCQI NTSV CL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | SGD; DAGD; 35DAG; CMD1L; SGCDP; LGMDR6; SG-delta; Delta-sarcoglycan (SGCD) |
Positive Sample: | Jurkat,THP-1,Mouse heart,Mouse skeletal muscle,Rat heart,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Single-pass type II membrane protein, cytoskeleton, sarcolemma. |
Calculated MW: | 32kDa |
Observed MW: | 37kDa |
The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6444 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |