def Antibody (PACO28862)
- SKU:
- PACO28862
- Product Type:
- Antibody
- Reactivity:
- Bacteria - Escherichia coli
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
def Antibody (PACO28862)
The DEF Antibody (PACO28862) is a specialized polyclonal antibody designed for research involving DEF, a cell surface molecule with implications in immune regulation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the DEF protein, this antibody enables the detection and analysis of DEF in various cell types, making it an ideal tool for studies in immunology and cancer research.DEF, also known as an immune modulator, plays a crucial role in immune system regulation by inhibiting immune responses. Its involvement in immune function makes it a valuable target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the mechanisms of DEF activity is essential for the development of therapies aimed at harnessing or modulating immune function in these disease contexts.Overall, the DEF Antibody (PACO28862) offers researchers a reliable tool for studying the function of DEF in immune regulation and its potential implications in various disease states. Its high reactivity and specificity make it an invaluable asset for advancing our understanding of immune modulation and developing targeted therapies for related conditions.
| Antibody Name: | def Antibody (PACO28862) |
| Antibody SKU: | PACO28862 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Escherichia coli |
| Immunogen: | Recombinant Escherichia coli Peptide deformylase protein (2-169AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: def antibody at 2µg/ml + DH5alpha whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 20 kDa Observed band size: 20 kDa . |
| Background: | Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. |
| Synonyms: | Peptide deformylase (PDF) (EC 3.5.1.88) (Polypeptide deformylase), def, fms |
| UniProt Protein Function: | Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. |
| UniProt Protein Details: | |
| NCBI Summary: | The def gene is essential unless the fmt formylase gene is also inactivated. [More information is available at EcoGene: EG11440]. Peptide deformylase releases the formyl group from the amino terminal methionine residue of most nascent proteins . [More information is available at EcoCyc: EG11440]. |
| UniProt Code: | P0A6K3 |
| NCBI GenInfo Identifier: | 16131166 |
| NCBI Gene ID: | 947780 |
| NCBI Accession: | NP_417745.1 |
| UniProt Secondary Accession: | P0A6K3,P27251, Q2M6V1 |
| UniProt Related Accession: | P0A6K3,CAA54826 |
| Molecular Weight: | 21.2 kDa |
| NCBI Full Name: | peptide deformylase |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | def  |
| NCBI Official Synonym Symbols: | ECK3273; fms; JW3248Â Â |
| NCBI Protein Information: | peptide deformylase |
| UniProt Protein Name: | Peptide deformylase |
| UniProt Synonym Protein Names: | Polypeptide deformylase |
| Protein Family: | Plectasin |
| UniProt Gene Name: | def  |
| UniProt Entry Name: | DEF_ECOLI |
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