The DECR2 Polyclonal Antibody (CAB17675) is a valuable tool for researchers studying DECR2, an enzyme involved in fatty acid metabolism and mitochondrial function. Raised in rabbits, this antibody is highly specific and reacts with human samples, making it ideal for use in Western blot applications. By binding to the DECR2 protein, this antibody enables precise detection and analysis in various cell types, facilitating studies in metabolic disorders, lipid metabolism, and mitochondrial dysfunction.DECR2, also known as 2,4-dienoyl-CoA reductase, plays a crucial role in the breakdown of unsaturated fatty acids and the production of energy in the mitochondria.
Dysregulation of DECR2 activity has been implicated in metabolic disorders such as fatty liver disease, diabetes, and obesity. Research into the function of DECR2 is essential for uncovering new therapeutic targets and interventions for these conditions.Overall, the DECR2 Polyclonal Antibody (CAB17675) provides researchers with a reliable tool for investigating the role of DECR2 in metabolic pathways and diseases related to fatty acid metabolism and mitochondrial dysfunction. Its high specificity and reactivity with human samples make it a valuable asset for studies aimed at understanding the molecular mechanisms underlying these conditions.
Product Name:
DECR2 Rabbit Polyclonal Antibody
SKU:
CAB17675
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human DECR2 (NP_065715.1).
Sequence:
GTFN VSRV LYEK FFRD HGGV IVNI TATL GNRG QALQ VHAG SAKA AVDA MTRH LAVE WGPQ NIRV NSLA PGPI SGTE GLRR LGGP QASL STKV TASP LQRL G
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
PDCR; SDR17C1; DECR2
Positive Sample:
HeLa,Mouse liver,Rat liver,Rat kidney
Conjugate:
Unconjugated
Cellular Localization:
cytosol, peroxisome
Calculated MW:
31kDa
Observed MW:
31kDa
Enables 2,4-dienoyl-CoA reductase (NADPH) activity and trans-2-enoyl-CoA reductase (NADPH) activity. Involved in unsaturated fatty acid biosynthetic process. Predicted to be located in peroxisome.
Purification Method:
Affinity purification
Gene ID:
26063
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DECR2 Rabbit pAb (CAB17675) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
